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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE1
All Species:
12.73
Human Site:
S216
Identified Species:
31.11
UniProt:
Q8IWY4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWY4
NP_766638.2
988
107910
S216
G
N
G
G
C
Q
H
S
C
E
D
T
D
T
G
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
S224
G
N
G
G
C
Q
H
S
C
D
D
T
A
D
G
Rhesus Macaque
Macaca mulatta
XP_001108689
995
108761
S216
G
N
G
G
C
Q
H
S
C
E
D
T
D
T
G
Dog
Lupus familis
XP_538874
1009
111038
T211
G
N
G
G
C
Q
H
T
C
D
D
T
E
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZL8
1018
111587
E246
R
T
C
I
E
K
D
E
A
A
I
E
R
S
Q
Rat
Rattus norvegicus
O88281
1574
165428
I261
G
N
G
G
C
M
H
I
C
Q
E
L
R
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
G170
T
V
N
G
P
E
C
G
C
H
P
K
Y
K
V
Chicken
Gallus gallus
O73775
704
78120
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
E240
R
T
C
V
E
R
D
E
M
A
P
T
A
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
I172
C
N
D
R
D
E
C
I
V
D
N
G
G
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.3
89.5
64.8
N.A.
89.2
22.4
N.A.
55.9
21.2
N.A.
64.6
N.A.
N.A.
N.A.
N.A.
43.3
Protein Similarity:
100
76.6
91.6
76.9
N.A.
92.6
31.8
N.A.
67.9
32.7
N.A.
77.2
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
80
100
73.3
N.A.
0
46.6
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
86.6
100
93.3
N.A.
13.3
60
N.A.
20
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
20
0
0
20
0
0
% A
% Cys:
10
0
20
0
50
0
20
0
60
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
10
0
20
0
0
30
40
0
20
10
10
% D
% Glu:
0
0
0
0
20
20
0
20
0
20
10
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
50
60
0
0
0
10
0
0
0
10
10
10
40
% G
% His:
0
0
0
0
0
0
50
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
20
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
60
10
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
20
0
0
10
0
% P
% Gln:
0
0
0
0
0
40
0
0
0
10
0
0
0
10
10
% Q
% Arg:
20
0
0
10
0
10
0
0
0
0
0
0
20
0
0
% R
% Ser:
0
0
0
0
0
0
0
30
0
0
0
0
0
10
10
% S
% Thr:
10
20
0
0
0
0
0
10
0
0
0
50
0
20
0
% T
% Val:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _